3TW8

GEF domain of DENND 1B in complex with Rab GTPase Rab35

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	DENN domain-containing protein 1B	polymer	391	44279.7	2	UniProt (Q6P3S1-2) Pfam (PF03456) Pfam (PF02141) Pfam (PF03455) UniProt (by SIFTS) (Q6P3S1)	Homo sapiens (human)	Connecdenn 2, Protein FAM31B
2	B, D (B, D)	Ras-related protein Rab-35	polymer	181	20623.3	2	UniProt (Q15286) Pfam (PF00071)	Homo sapiens (human)	GTP-binding protein RAY, Ras-related protein Rab-1C
3	E, F, G, H (A, B, C, D)	water	water		18.0	187	Chemie (HOH)

Sequence modifications

A, C: 2 - 391 (UniProt: Q6P3S1-2)

PDB	External Database	Details
Ser 1	-	expression tag

B, D: 1 - 180 (UniProt: Q15286)

PDB	External Database	Details
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	129806.0
All*	Total formula weight	129806.0

*Water molecules are not included.