3TU1
Exhaustive Fluorine Scanning towards Potent p53-MDM2 Antagonist
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | E3 ubiquitin-protein ligase Mdm2 | polymer | 108 | 12448.3 | 1 | UniProt (Q00987) Pfam (PF02201) | Homo sapiens (human) | Double minute 2 protein, Hdm2, Oncoprotein Mdm2, p53-binding protein Mdm2 |
| 2 | B (A) | 3-[(1S)-2-(tert-butylamino)-1-{N-[(3,4-difluorophenyl)methyl]formamido}-2-oxoethyl]-6-chloro-1H-indole-2-carboxylic acid | non-polymer | 477.9 | 1 | Chemie (07G) | |||
| 3 | C (A) | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 12448.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 477.9 | |
| All* | Total formula weight | 12926.2 |
