3TPX
Crystal structure of human MDM2 in complex with a trifluoromethylated D-peptide inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E | E3 ubiquitin-protein ligase Mdm2 | polymer | 85 | 10044.9 | 3 | UniProt (Q00987) Pfam (PF02201) In PDB | Homo sapiens | Double minute 2 protein, Hdm2, Oncoprotein Mdm2, p53-binding protein Mdm2 |
| 2 | B, D, F | D-peptide inhibitor DPMI-delta | polymer | 12 | 1580.7 | 3 | BIRD (PRD_000995) | ||
| 3 | A, C | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 4 | C, E | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 5 | C, E | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 6 | water | water | 18.0 | 225 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 34876.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 701.6 | |
| All* | Total formula weight | 35578.5 |
