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3THP

Crystal structure and RNA binding properties of the RRM/AlkB domains in human ABH8, an enzyme catalyzing tRNA hypermodification, Northeast Structural Genomics Consortium Target HR5601B

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Alkylated DNA repair protein alkB homolog 8polymer34539687.91UniProt (Q96BT7)
Pfam (PF09004)
Pfam (PF00076)
Pfam (PF13532)
Homo sapiens (human)Probable alpha-ketoglutarate-dependent dioxygenase ABH8
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
MANGANESE (II) IONnon-polymer54.91Chemie (MN)
4D
(A)
2-OXOGLUTARIC ACIDnon-polymer146.11Chemie (AKG)
Sequence modifications
A: 25 - 355 (UniProt: Q96BT7)
PDBExternal DatabaseDetails
Asn 356-expression tag
Leu 357-expression tag
Tyr 358-expression tag
Phe 359-expression tag
Gln 360-expression tag
Gly 361-expression tag
Leu 362-expression tag
Glu 363-expression tag
His 364-expression tag
His 365-expression tag
His 366-expression tag
His 367-expression tag
His 368-expression tag
His 369-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39687.9
Non-Polymers*Number of molecules3
Total formula weight266.4
All*Total formula weight39954.4
*Water molecules are not included.

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PDB entries from 2024-11-06

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