3TGX
IL-21:IL21R complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... (A, C, E, G, I...) | Interleukin-21 receptor | polymer | 219 | 25451.3 | 8 | UniProt (Q9HBE5) | Homo sapiens (human) | IL-21 receptor, IL-21R, Novel interleukin receptor |
| 2 | B, D, F, H, J... (B, D, F, H, J...) | Interleukin-21 | polymer | 134 | 15622.9 | 8 | UniProt (Q9HBE4) Pfam (PF02372) | Homo sapiens (human) | IL-21, Za11 |
| 3 | Q, R, S, T, U (Q, R, S, T, U) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1219.1 | 5 | In PDB GlyTouCan (G86836LG) | |||
| 4 | V, X (V, X) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 2 | In PDB GlyTouCan (G39569XI) | |||
| 5 | W (W) | alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 1 | In PDB GlyTouCan (G52146XU) | |||
| 6 | EB, KA, LA, LB, QB... (K, C, E, M, O...) | alpha-D-mannopyranose | non-polymer | 180.2 | 8 | Chemie (MAN) | |||
| 7 | MA, RB, SA, Z (E, O, G, A) | NICKEL (II) ION | non-polymer | 58.7 | 4 | Chemie (NI) | |||
| 8 | AA, AB, BA, BB, CA... (A, I, C, K, L...) | SULFATE ION | non-polymer | 96.1 | 39 | Chemie (SO4) |
Sequence modifications
A, C, E, G, I, K, M, O: 1 - 213 (UniProt: Q9HBE5)
B, D, F, H, J, L, N, P: 1 - 133 (UniProt: Q9HBE4)
| PDB | External Database | Details |
|---|---|---|
| Gln 78 | Asn 97 | engineered mutation |
| Gln 85 | Asn 104 | engineered mutation |
| Asp 106 | Asn 125 | engineered mutation |
| Gln 116 | Asn 135 | engineered mutation |
| His 214 | - | expression tag |
| His 215 | - | expression tag |
| His 216 | - | expression tag |
| His 217 | - | expression tag |
| His 218 | - | expression tag |
| His 219 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 328593.5 | |
| Branched | Number of molecules | 8 |
| Total formula weight | 9266.4 | |
| Non-Polymers* | Number of molecules | 51 |
| Total formula weight | 5422.5 | |
| All* | Total formula weight | 343282.4 |
