3SZR

Crystal structure of modified nucleotide-free human MxA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Interferon-induced GTP-binding protein Mx1	polymer	608	69176.8	1	UniProt (P20591) Pfam (PF00350) Pfam (PF01031) Pfam (PF02212) In PDB	Homo sapiens (human)	Interferon-induced protein p78, IFI-78K, Interferon-regulated resistance GTP-binding protein MxA, Myxoma resistance protein 1, Myxovirus resistance protein 1, Interferon-induced GTP-binding protein Mx1, N-terminally processed

Sequence modifications

A: 33 - 662 (UniProt: P20591)

PDB	External Database	Details
Gly 26	-	expression tag
Pro 27	-	expression tag
His 28	-	expression tag
Met 29	-	expression tag
Gly 30	-	expression tag
Gly 31	-	expression tag
Ser 32	-	expression tag
Ala 440	Tyr 440	engineered mutation
Ala 441	Arg 441	engineered mutation
Ala 442	Gly 442	engineered mutation
Ala 443	Arg 443	engineered mutation
-	Cys 533	deletion
-	Gln 534	deletion
-	Asp 535	deletion
-	Gln 536	deletion
-	Val 537	deletion
-	Tyr 538	deletion
-	Arg 539	deletion
-	Gly 540	deletion
-	Ala 541	deletion
-	Leu 542	deletion
-	Gln 543	deletion
-	Lys 544	deletion
-	Val 545	deletion
-	Arg 546	deletion
-	Glu 547	deletion
-	Lys 548	deletion
-	Glu 549	deletion
-	Leu 550	deletion
-	Glu 551	deletion
-	Glu 552	deletion
-	Glu 553	deletion
-	Lys 554	deletion
-	Lys 555	deletion
-	Lys 556	deletion
-	Lys 557	deletion
-	Ser 558	deletion
-	Trp 559	deletion
-	Asp 560	deletion
-	Phe 561	deletion

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	69176.8
All*	Total formula weight	69176.8

*Water molecules are not included.