3SZR
Crystal structure of modified nucleotide-free human MxA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0002376 | biological_process | immune system process |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005635 | cellular_component | nuclear envelope |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0005829 | cellular_component | cytosol |
| A | 0005874 | cellular_component | microtubule |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006915 | biological_process | apoptotic process |
| A | 0006952 | biological_process | defense response |
| A | 0007165 | biological_process | signal transduction |
| A | 0008017 | molecular_function | microtubule binding |
| A | 0009615 | biological_process | response to virus |
| A | 0016185 | biological_process | synaptic vesicle budding from presynaptic endocytic zone membrane |
| A | 0031965 | cellular_component | nuclear membrane |
| A | 0034340 | biological_process | response to type I interferon |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0045071 | biological_process | negative regulation of viral genome replication |
| A | 0045087 | biological_process | innate immune response |
| A | 0045202 | cellular_component | synapse |
| A | 0048471 | cellular_component | perinuclear region of cytoplasm |
| A | 0051607 | biological_process | defense response to virus |
| A | 0070106 | biological_process | interleukin-27-mediated signaling pathway |
| A | 0098793 | cellular_component | presynapse |
| A | 0140374 | biological_process | antiviral innate immune response |
Functional Information from PROSITE/UniProt
| site_id | PS00410 |
| Number of Residues | 10 |
| Details | G_DYNAMIN_1 Dynamin-type guanine nucleotide-binding (G) domain signature. LPRGSGIVTR |
| Chain | Residue | Details |
| A | LEU95-ARG104 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 88 |
| Details | Domain: {"description":"GED","evidences":[{"source":"PROSITE-ProRule","id":"PRU00720","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Region: {"description":"G1 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Region: {"description":"G2 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Region: {"description":"G3 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Region: {"description":"G4 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | Region: {"description":"G5 motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU01055","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 25 |
| Details | Region: {"description":"Bundle signaling element (BSE)"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
