3SOM

crystal structure of human MMACHC

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Methylmalonic aciduria and homocystinuria type C protein	polymer	286	32432.6	16	UniProt (Q9Y4U1) Pfam (PF16690)	Homo sapiens (human)
2	AC, CA, CB, FA, FB... (P, D, J, E, K...)	COBALAMIN	non-polymer		1330.4	16	Chemie (B12)
3	BC, DA, DB, GA, GB... (P, D, J, E, K...)	CITRATE ANION	non-polymer		189.1	16	Chemie (FLC) PubChem (31348)
4	CC, EA, EB, HB, MA... (P, D, J, K, F...)	2-AMINO-ETHANETHIOL	non-polymer		77.1	14	Chemie (DHL)
5	AA, AB, BA, BB, HA... (C, I, D, J, E...)	5'-DEOXYADENOSINE	non-polymer		251.2	18	Chemie (5AD) PubChem (16725083) PubChem (142) PubChem (23638944) PubChem (25201172) PubChem (25796474) PubChem (25796475) PubChem (40467848) PubChem (71678) PubChem (23615209) PubChem (40467849) PubChem (57115448) PubChem (439182) PubChem (59731278) PubChem (449044) PubChem (1277776) PubChem (90321697) PubChem (676784) PubChem (6541038) PubChem (6398669) PubChem (6928544) PubChem (121275112) PubChem (124363198) PubChem (12827542) PubChem (133636852) PubChem (140689696) PubChem (142801875) PubChem (142801934)
6	DC, EC, IA (P, E)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
7	FC, GC, HC, IC, JC... (A, B, C, D, E...)	water	water		18.0	1646	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P: 1 - 282 (UniProt: Q9Y4U1)

PDB	External Database	Details
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	518921.6
Non-Polymers*	Number of molecules	67
	Total formula weight	30099.9
All*	Total formula weight	549021.5

*Water molecules are not included.