3SIP

Crystal structure of drICE and dIAP1-BIR1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, C)	Caspase	polymer	157	17908.2	2	UniProt (O01382) Pfam (PF00656)	Drosophila melanogaster (Fruit fly)	drICE large subunit, drICE, Caspase subunit p21, Caspase subunit p12
2	C, D (E, F)	Apoptosis 1 inhibitor	polymer	115	13423.0	2	UniProt (Q24306) Pfam (PF00653)	Drosophila melanogaster (Fruit fly)	dIAP1-BIR1, E3 ubiquitin-protein ligase th, Inhibitor of apoptosis 1, dIAP1, Protein thread
3	E, F (B, D)	Caspase	polymer	109	12305.2	2	UniProt (O01382) Pfam (PF00656)	Drosophila melanogaster (Fruit fly)	drICE small subunit, drICE, Caspase subunit p21, Caspase subunit p12
4	G, H (E, F)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A, C: 5 - 157 (UniProt: O01382)

PDB	External Database	Details
Ala 1	-	SEE REMARK 999
Leu 2	-	SEE REMARK 999
Gly 3	-	SEE REMARK 999
Ser 4	-	SEE REMARK 999

E, F: 31 - 145 (UniProt: Q24306)

PDB	External Database	Details
Ser 89	Cys 89	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	87272.8
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	87403.6

*Water molecules are not included.