3SIP

Crystal structure of drICE and dIAP1-BIR1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Caspase	polymer	157	17908.2	2	UniProt (O01382) Pfam (PF00656) In PDB	Drosophila melanogaster (Fruit fly)	drICE large subunit, drICE, Caspase subunit p21, Caspase subunit p12
2	E, F	Apoptosis 1 inhibitor	polymer	115	13423.0	2	UniProt (Q24306) Pfam (PF00653) In PDB	Drosophila melanogaster (Fruit fly)	dIAP1-BIR1, E3 ubiquitin-protein ligase th, Inhibitor of apoptosis 1, dIAP1, Protein thread
3	B, D	Caspase	polymer	109	12305.2	2	UniProt (O01382) Pfam (PF00656) In PDB	Drosophila melanogaster (Fruit fly)	drICE small subunit, drICE, Caspase subunit p21, Caspase subunit p12
4	E, F	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A, C: 5 - 157 (UniProt: O01382)

PDB	External Database	Details
Ala 1	-	SEE REMARK 999
Leu 2	-	SEE REMARK 999
Gly 3	-	SEE REMARK 999
Ser 4	-	SEE REMARK 999

E, F: 31 - 145 (UniProt: Q24306)

PDB	External Database	Details
Ser 89	Cys 89	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	87272.8
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	87403.6

*Water molecules are not included.