3SIP

Crystal structure of drICE and dIAP1-BIR1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004197	molecular_function	cysteine-type endopeptidase activity
A	0006508	biological_process	proteolysis
A	0008234	molecular_function	cysteine-type peptidase activity
B	0004197	molecular_function	cysteine-type endopeptidase activity
B	0006508	biological_process	proteolysis
B	0008234	molecular_function	cysteine-type peptidase activity
C	0004197	molecular_function	cysteine-type endopeptidase activity
C	0006508	biological_process	proteolysis
C	0008234	molecular_function	cysteine-type peptidase activity
D	0004197	molecular_function	cysteine-type endopeptidase activity
D	0006508	biological_process	proteolysis
D	0008234	molecular_function	cysteine-type peptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 1

Chain	Residue
E	CYS80
E	CYS83
E	HIS100
E	CYS107

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 1

Chain	Residue
F	CYS80
F	CYS83
F	HIS100
F	CYS107

---

Functional Information from PROSITE/UniProt

site_id	PS01121
Number of Residues	15
Details	CASPASE_HIS Caspase family histidine active site. HsdsdCilVaILSHG

Chain	Residue	Details
A	HIS83-GLY97

---

site_id	PS01122
Number of Residues	12
Details	CASPASE_CYS Caspase family cysteine active site. KPKLFFIQACQG

Chain	Residue	Details
A	LYS129-GLY140

---

site_id	PS01282
Number of Residues	67
Details	BIR_REPEAT_1 BIR repeat. EetRlktftd.Wpldwldkrqlaq..TGMyFthagDkvkCffCgveigsWeqedqpvpeHqrwsPnCplL

Chain	Residue	Details
E	GLU44-LEU110

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	132
Details	Repeat: {"description":"BIR 1"}

Chain

Residue

Details

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