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3SFY

Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and ethylenediamine inhibitor 2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cryptococcus neoformans protein farnesyltransferase alpha subunitpolymer34940927.31Cryptococcus neoformans
2B
(B)
Cryptococcus neoformans protein farnesyltransferase beta subunitpolymer52056806.91Cryptococcus neoformans
3C
(B)
ZINC IONnon-polymer65.41Chemie (ZN)
4D, E, F
(B)
(2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acidnon-polymer237.33Chemie (3FX)
5G
(B)
N-(2-{(4-bromophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)-1-methyl-N-(2-methylbenzyl)-1H-imidazole-4-sulfonamidenon-polymer557.51Chemie (3FY)
6H
(B)
[(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACIDnon-polymer359.41Chemie (FII)
7I
(B)
SULFATE IONnon-polymer96.11Chemie (SO4)
8J, K
(A, B)
waterwater18.0646Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight97734.1
Non-Polymers*Number of molecules7
Total formula weight1790.3
All*Total formula weight99524.5
*Water molecules are not included.

237992

PDB entries from 2025-06-25

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