3SFX
Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and tipifarnib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cryptococcus neoformans protein farnesyltransferase alpha subunit | polymer | 349 | 40927.3 | 1 | Cryptococcus neoformans | ||
| 2 | B | Cryptococcus neoformans protein farnesyltransferase beta subunit | polymer | 520 | 56806.9 | 1 | Cryptococcus neoformans | ||
| 3 | B | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | B | (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid | non-polymer | 237.3 | 3 | Chemie (3FX) | |||
| 5 | B | [(3,7,11-TRIMETHYL-DODECA-2,6,10-TRIENYLOXYCARBAMOYL)-METHYL]-PHOSPHONIC ACID | non-polymer | 359.4 | 1 | Chemie (FII) | |||
| 6 | B | 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE | non-polymer | 489.4 | 1 | Chemie (JAN) | |||
| 7 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 8 | water | water | 18.0 | 669 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 97734.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1722.2 | |
| All* | Total formula weight | 99456.4 |
