3SBC

Crystal structure of Saccharomyces cerevisiae TSA1C47S mutant protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Peroxiredoxin TSA1	polymer	216	23766.9	10	UniProt (P34760) Pfam (PF00578) Pfam (PF10417) In PDB	Saccharomyces cerevisiae (Baker's yeast)	Cytoplasmic thiol peroxidase 1, cTPx 1, PRP, Thiol-specific antioxidant protein 1, Thioredoxin peroxidase
2	B, E, G, H, J	(2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL	non-polymer		154.3	5	Chemie (DTU)
3	C	(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL	non-polymer		154.3	1	Chemie (DTV)
4		water	water		18.0	352	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J: 0 - 195 (UniProt: P34760)

PDB	External Database	Details
Met -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Ser 47	Cys 48	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	237669.5
Non-Polymers*	Number of molecules	6
	Total formula weight	925.5
All*	Total formula weight	238595.0

*Water molecules are not included.