3S3X

Structure of chicken acid-sensing ion channel 1 AT 3.0 A resolution in complex with psalmotoxin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Amiloride-sensitive cation channel 2, neuronal	polymer	459	52622.8	3	UniProt (Q1XA76) Pfam (PF00858) In PDB	Gallus gallus (bantam chickens)	Acid-sensing ion channel 1
2	D, E, F	Psalmotoxin-1	polymer	37	4346.1	3	UniProt (P60514) In PDB	Psalmopoeus cambridgei	Pi-TRTX-Pc1a, PcTx1, Pi-theraphotoxin-Pc1a
3	A, B, C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)
4	A	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
5	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
6	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
7		water	water		18.0	14	Chemie (HOH)

Sequence modifications

A, B, C: 26 - 463 (UniProt: Q1XA76)

PDB	External Database	Details
Met 5	-	expression tag
Ser 6	-	expression tag
Tyr 7	-	expression tag
Tyr 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
Gly 15	-	expression tag
Ala 16	-	expression tag
Ser 17	-	expression tag
Leu 18	-	expression tag
Val 19	-	expression tag
Pro 20	-	expression tag
Arg 21	-	expression tag
Gly 22	-	expression tag
Ser 23	-	expression tag
His 24	-	expression tag
Met 25	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	170906.9
Non-Polymers*	Number of molecules	10
	Total formula weight	1537.0
All*	Total formula weight	172443.8

*Water molecules are not included.