3RL0
Truncated SNARE complex with complexin (P1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, CA, E, I, M... (A, E, I, M, Q...) | Vesicle-associated membrane protein 2 | polymer | 37 | 4254.8 | 8 | UniProt (P63027) Pfam (PF00957) | Homo sapiens (human) | VAMP-2, Synaptobrevin-2 |
| 2 | B, DA, F, J, N... (B, F, J, N, R...) | Syntaxin-1A | polymer | 65 | 7551.5 | 8 | UniProt (P32851) Pfam (PF05739) | Rattus norvegicus (brown rat rat rats) | Neuron-specific antigen HPC-1, Synaptotagmin-associated 35 kDa protein, P35A |
| 3 | AA, C, EA, G, K... (C, G, K, O, S...) | Synaptosomal-associated protein 25 | polymer | 81 | 9500.6 | 8 | UniProt (P60880) | Homo sapiens (human) | SNAP-25, Super protein, SUP, Synaptosomal-associated 25 kDa protein |
| 4 | BA, D, FA, H, L... (D, H, L, P, T...) | Synaptosomal-associated protein 25 | polymer | 65 | 7427.3 | 8 | UniProt (P60880) | Homo sapiens (human) | SNAP-25, Super protein, SUP, Synaptosomal-associated 25 kDa protein |
| 5 | GA, HA, IA, JA, KA... (g, h, i, j, k...) | Complexin-1 | polymer | 63 | 7313.0 | 8 | UniProt (O14810) Pfam (PF05835) | Homo sapiens (human) | Complexin I, CPX I, Synaphin-2 |
Sequence modifications
A, E, I, M, Q, U, Y, c: 28 - 60 (UniProt: P63027)
B, F, J, N, R, V, Z, d: 191 - 253 (UniProt: P32851)
C, G, K, O, S, W, a, e: 7 - 82 (UniProt: P60880)
D, H, L, P, T, X, b, f: 141 - 203 (UniProt: P60880)
g, h, i, j, k, l, m, n: 26 - 83 (UniProt: O14810)
| PDB | External Database | Details |
|---|---|---|
| Gly 24 | - | expression tag |
| Pro 25 | - | expression tag |
| Leu 26 | - | expression tag |
| Gly 27 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 189 | - | expression tag |
| Ser 190 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 3 | - | expression tag |
| Ser 4 | - | expression tag |
| His 5 | - | expression tag |
| Met 6 | - | expression tag |
| Trp 83 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 139 | - | expression tag |
| Ser 140 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 21 | - | expression tag |
| Pro 22 | - | expression tag |
| Leu 23 | - | expression tag |
| Gly 24 | - | expression tag |
| Ser 25 | - | expression tag |
| Leu 27 | Asp 27 | engineered mutation |
| Mse 34 | Glu 34 | engineered mutation |
| Ala 37 | Arg 37 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 40 |
| Total formula weight | 288377.2 | |
| All* | Total formula weight | 288377.2 |
