Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3RL0

Truncated SNARE complex with complexin (P1)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
A	0016192	biological_process	vesicle-mediated transport
B	0005484	molecular_function	SNAP receptor activity
B	0006886	biological_process	intracellular protein transport
B	0016020	cellular_component	membrane
B	0016192	biological_process	vesicle-mediated transport
C	0000149	molecular_function	SNARE binding
C	0005249	molecular_function	voltage-gated potassium channel activity
C	0017075	molecular_function	syntaxin-1 binding
E	0016020	cellular_component	membrane
E	0016192	biological_process	vesicle-mediated transport
F	0005484	molecular_function	SNAP receptor activity
F	0006886	biological_process	intracellular protein transport
F	0016020	cellular_component	membrane
F	0016192	biological_process	vesicle-mediated transport
G	0000149	molecular_function	SNARE binding
G	0005249	molecular_function	voltage-gated potassium channel activity
G	0017075	molecular_function	syntaxin-1 binding
I	0016020	cellular_component	membrane
I	0016192	biological_process	vesicle-mediated transport
J	0005484	molecular_function	SNAP receptor activity
J	0006886	biological_process	intracellular protein transport
J	0016020	cellular_component	membrane
J	0016192	biological_process	vesicle-mediated transport
K	0000149	molecular_function	SNARE binding
K	0005249	molecular_function	voltage-gated potassium channel activity
K	0017075	molecular_function	syntaxin-1 binding
M	0016020	cellular_component	membrane
M	0016192	biological_process	vesicle-mediated transport
N	0005484	molecular_function	SNAP receptor activity
N	0006886	biological_process	intracellular protein transport
N	0016020	cellular_component	membrane
N	0016192	biological_process	vesicle-mediated transport
O	0000149	molecular_function	SNARE binding
O	0005249	molecular_function	voltage-gated potassium channel activity
O	0017075	molecular_function	syntaxin-1 binding
Q	0016020	cellular_component	membrane
Q	0016192	biological_process	vesicle-mediated transport
R	0005484	molecular_function	SNAP receptor activity
R	0006886	biological_process	intracellular protein transport
R	0016020	cellular_component	membrane
R	0016192	biological_process	vesicle-mediated transport
S	0000149	molecular_function	SNARE binding
S	0005249	molecular_function	voltage-gated potassium channel activity
S	0017075	molecular_function	syntaxin-1 binding
U	0016020	cellular_component	membrane
U	0016192	biological_process	vesicle-mediated transport
V	0005484	molecular_function	SNAP receptor activity
V	0006886	biological_process	intracellular protein transport
V	0016020	cellular_component	membrane
V	0016192	biological_process	vesicle-mediated transport
W	0000149	molecular_function	SNARE binding
W	0005249	molecular_function	voltage-gated potassium channel activity
W	0017075	molecular_function	syntaxin-1 binding
Y	0016020	cellular_component	membrane
Y	0016192	biological_process	vesicle-mediated transport
Z	0005484	molecular_function	SNAP receptor activity
Z	0006886	biological_process	intracellular protein transport
Z	0016020	cellular_component	membrane
Z	0016192	biological_process	vesicle-mediated transport
a	0000149	molecular_function	SNARE binding
a	0005249	molecular_function	voltage-gated potassium channel activity
a	0017075	molecular_function	syntaxin-1 binding
c	0016020	cellular_component	membrane
c	0016192	biological_process	vesicle-mediated transport
d	0005484	molecular_function	SNAP receptor activity
d	0006886	biological_process	intracellular protein transport
d	0016020	cellular_component	membrane
d	0016192	biological_process	vesicle-mediated transport
e	0000149	molecular_function	SNARE binding
e	0005249	molecular_function	voltage-gated potassium channel activity
e	0017075	molecular_function	syntaxin-1 binding
g	0006836	biological_process	neurotransmitter transport
g	0019905	molecular_function	syntaxin binding
h	0006836	biological_process	neurotransmitter transport
h	0019905	molecular_function	syntaxin binding
i	0006836	biological_process	neurotransmitter transport
i	0019905	molecular_function	syntaxin binding
j	0006836	biological_process	neurotransmitter transport
j	0019905	molecular_function	syntaxin binding
k	0006836	biological_process	neurotransmitter transport
k	0019905	molecular_function	syntaxin binding
l	0006836	biological_process	neurotransmitter transport
l	0019905	molecular_function	syntaxin binding
m	0006836	biological_process	neurotransmitter transport
m	0019905	molecular_function	syntaxin binding
n	0006836	biological_process	neurotransmitter transport
n	0019905	molecular_function	syntaxin binding

Functional Information from PROSITE/UniProt

site_id	PS00914
Number of Residues	40
Details	SYNTAXIN Syntaxin / epimorphin family signature. RhseIikLEnsIrELhdMFmdMamlVesQGemIDrIEyn.V

Chain	Residue	Details
B	ARG198-VAL237

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Site: {"description":"(Microbial infection) Cleavage; by C.botulinum neurotoxin type F (BoNT/F, botF)","evidences":[{"source":"PubMed","id":"19543288","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	62
Details	Domain: {"description":"t-SNARE coiled-coil homology 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00202","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	8
Details	Site: {"description":"(Microbial infection) Cleavage; by C.botulinum neurotoxin type E (BoNT/E)","evidences":[{"source":"PubMed","id":"9886085","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	8
Details	Site: {"description":"(Microbial infection) Cleavage; by C.botulinum neurotoxin type A (BoNT/A, botA)","evidences":[{"source":"PubMed","id":"9886085","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15592454","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	8
Details	Site: {"description":"(Microbial infection) Cleavage; by C.botulinum neurotoxin type C (BoNT/C)","evidences":[{"source":"PubMed","id":"9886085","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15592454","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	16
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P60879","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)