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3QU6

Crystal structure of IRF-3 DBD free form

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
IRF3 proteinpolymer11613416.23UniProt (Q7Z5G6)
Pfam (PF00605)
UniProt (by SIFTS) (Q14653)
Homo sapiens (human)
2D, E, F, G, N...
(A, B, C)
ZINC IONnon-polymer65.49Chemie (ZN)
3H, I, J, M, P...
(A, B, C)
CHLORIDE IONnon-polymer35.57Chemie (CL)
4K, L, Q
(A, B)
SODIUM IONnon-polymer23.03Chemie (NA)
5W, X, Y
(A, B, C)
waterwater18.0151Chemie (HOH)
Sequence modifications
A, B, C: 1 - 113 (UniProt: Q7Z5G6)
PDBExternal DatabaseDetails
Gly -2-expression tag
Ser -1-expression tag
His 0-expression tag
Met 84Leu 84engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight40248.5
Non-Polymers*Number of molecules19
Total formula weight905.8
All*Total formula weight41154.3
*Water molecules are not included.

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PDB entries from 2026-01-14

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