3QIP
Structure of HIV-1 reverse transcriptase in complex with an RNase H inhibitor and nevirapine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Reverse HIV-1 reverse transcriptase p66 | polymer | 560 | 64562.9 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075) | HIV-1 M:B_HXB2R (HIV-1) | Pr160Gag-Pol, Matrix protein p17, MA, Capsid protein p24, CA, Spacer peptide p2, Nucleocapsid protein p7, NC, Transframe peptide, TF, p6-pol, p6*, Protease, PR, Retropepsin, Reverse transcriptase/ribonuclease H, p66 RT, p51 RT, p15, Integrase, IN |
| 2 | B (B) | p51 | polymer | 440 | 51399.0 | 1 | UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) | HIV-1 M:B_HXB2R (HIV-1) | Pr160Gag-Pol, Matrix protein p17, MA, Capsid protein p24, CA, Spacer peptide p2, Nucleocapsid protein p7, NC, Transframe peptide, TF, p6-pol, p6*, Protease, PR, Retropepsin, Reverse transcriptase/ribonuclease H, p66 RT, p51 RT, p15, Integrase, IN |
| 3 | C (A) | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE | non-polymer | 266.3 | 1 | Chemie (NVP) | |||
| 4 | D, E (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 5 | F, G (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | H, J (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 7 | I (A) | 5,6-dihydroxy-2-[(2-phenyl-1H-indol-3-yl)methyl]pyrimidine-4-carboxylic acid | non-polymer | 361.4 | 1 | Chemie (P4Y) | |||
| 8 | K, L (A, B) | water | water | 18.0 | 418 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115962.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1000.6 | |
| All* | Total formula weight | 116962.6 |
