3QI0

Structural, thermodynamic and kinetic analysis of the picomolar binding affinity interaction of the beta-lactamase inhibitor protein-II (BLIP-II) with class A beta-lactamases

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Beta-lactamase inhibitory protein II	polymer	282	28360.9	6	UniProt (O87916) Pfam (PF13540) In PDB	Streptomyces exfoliatus (Streptomyces hydrogenans)
2	D, E, A, B, F...	SULFATE ION	non-polymer		96.1	35	Chemie (SO4)
3		water	water		18.0	199	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 41 - 311 (UniProt: O87916)

PDB	External Database	Details
Gly 312	-	expression tag
Ser 313	-	expression tag
Gly 314	-	expression tag
Ser 315	-	expression tag
Gly 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag
His 319	-	expression tag
His 320	-	expression tag
His 321	-	expression tag
His 322	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	170165.7
Non-Polymers*	Number of molecules	35
	Total formula weight	3362.2
All*	Total formula weight	173527.9

*Water molecules are not included.