3QI0

Structural, thermodynamic and kinetic analysis of the picomolar binding affinity interaction of the beta-lactamase inhibitor protein-II (BLIP-II) with class A beta-lactamases

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0046872	molecular_function	metal ion binding
B	0046872	molecular_function	metal ion binding
C	0046872	molecular_function	metal ion binding
D	0046872	molecular_function	metal ion binding
E	0046872	molecular_function	metal ion binding
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 4

Chain	Residue
A	PRO98
A	ALA99

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 11

Chain	Residue
A	PRO59
A	ALA60

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 15

Chain	Residue
A	TRP47
A	GLY48

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 23

Chain	Residue
A	ALA89
A	ASN90

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 25

Chain	Residue
A	ALA177
A	PRO176

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 26

Chain	Residue
A	PRO215
A	ALA216

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 1

Chain	Residue
A	GLY48
A	GLY49
A	ARG286
A	HOH351

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 3

Chain	Residue
B	PRO98
B	ALA99

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 7

Chain	Residue
B	PRO59
B	ALA60

---

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 B 10

Chain	Residue
B	ALA177

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 19

Chain	Residue
B	TRP47
B	GLY48
B	GLY49

---

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 21

Chain	Residue
B	PRO215
B	ALA216

---

site_id	BC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 24

Chain	Residue
B	GLU178
B	LYS197

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 31

Chain	Residue
B	ALA138
B	ARG141
C	SER294
C	LYS310

---

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 2

Chain	Residue
B	GLY48
B	GLY49
B	ARG286

---

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 6

Chain	Residue
C	PRO137
C	ALA138

---

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 8

Chain	Residue
C	THR213
C	VAL214

---

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 12

Chain	Residue
C	PRO176
C	ALA177

---

site_id	CC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 3

Chain	Residue
C	PRO98
C	ALA99

---

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 1

Chain	Residue
D	PRO98
D	ALA99

---

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 9

Chain	Residue
D	PRO176
D	ALA177

---

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 13

Chain	Residue
D	PRO137
D	ALA138
D	HOH328

---

site_id	CC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 14

Chain	Residue
D	GLY48
D	GLY49
D	ARG286

---

site_id	CC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 16

Chain	Residue
D	THR213
D	VAL214

---

site_id	CC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 27

Chain	Residue
D	SER294
D	GLY295
D	LYS310
F	ALA138
F	ARG141

---

site_id	CC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 2

Chain	Residue
E	PRO98
E	ALA99

---

site_id	CC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 5

Chain	Residue
A	ARG141
E	SER294
E	GLY295
E	LYS310

---

site_id	DC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 17

Chain	Residue
E	TYR248
E	TRP269
E	SER284

---

site_id	DC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 18

Chain	Residue
E	GLY48
E	GLY49
E	ARG286

---

site_id	DC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 20

Chain	Residue
E	PRO176
E	ALA177

---

site_id	DC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 22

Chain	Residue
E	SER142
E	GLY143
E	LYS158

---

site_id	DC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 28

Chain	Residue
E	SER103
E	GLY104
E	LYS119

---

site_id	DC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 29

Chain	Residue
E	PRO137
E	ALA138

---

site_id	DC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 F 30

Chain	Residue
F	GLY48
F	GLY49
F	SER284
F	ARG286

---

site_id	DC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 F 32

Chain	Residue
F	PRO176
F	ALA177

---

Functional Information from PROSITE/UniProt

site_id	PS00626
Number of Residues	11
Details	RCC1_2 Regulator of chromosome condensation (RCC1) signature 2. IAGGyFHGLAL

Chain	Residue	Details
A	ILE69-LEU79
A	ILE108-LEU118
A	VAL225-LEU235

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