3QF7

The Mre11:Rad50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Rad50	polymer	365	41073.9	2	UniProt (Q9X1X1) Pfam (PF13476) Pfam (PF13558) In PDB	Thermotoga maritima
2	D, C	Mre11	polymer	50	6237.1	2	UniProt (Q9X1X0) Pfam (PF22161) In PDB	Thermotoga maritima
3	A, B	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)
4	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5		water	water		18.0	487	Chemie (HOH)

Sequence modifications

A, B: 1 - 190 (UniProt: Q9X1X1)
A, B: 686 - 852 (UniProt: Q9X1X1)

PDB	External Database	Details
Gly 678	-	linker
Gly 679	-	linker
Ala 680	-	linker
Gly 681	-	linker
Gly 682	-	linker
Ala 683	-	linker
Gly 684	-	linker
Gly 685	-	linker

D, C: 343 - 385 (UniProt: Q9X1X0)

PDB	External Database	Details
Gly 386	-	expression tag
His 387	-	expression tag
His 388	-	expression tag
His 389	-	expression tag
His 390	-	expression tag
His 391	-	expression tag
His 392	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	94621.9
Non-Polymers*	Number of molecules	4
	Total formula weight	1061.0
All*	Total formula weight	95682.9

*Water molecules are not included.