3QF7
The Mre11:Rad50 complex forms an ATP dependent molecular clamp in DNA double-strand break repair
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Rad50 | polymer | 365 | 41073.9 | 2 | UniProt (Q9X1X1) Pfam (PF13476) Pfam (PF13558) | Thermotoga maritima | |
| 2 | C, D (D, C) | Mre11 | polymer | 50 | 6237.1 | 2 | UniProt (Q9X1X0) Pfam (PF22161) | Thermotoga maritima | |
| 3 | E, G (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 4 | F, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | I, J, K, L (A, B, D, C) | water | water | 18.0 | 487 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 190 (UniProt: Q9X1X1)
A, B: 686 - 852 (UniProt: Q9X1X1)
D, C: 343 - 385 (UniProt: Q9X1X0)
A, B: 686 - 852 (UniProt: Q9X1X1)
| PDB | External Database | Details |
|---|---|---|
| Gly 678 | - | linker |
| Gly 679 | - | linker |
| Ala 680 | - | linker |
| Gly 681 | - | linker |
| Gly 682 | - | linker |
| Ala 683 | - | linker |
| Gly 684 | - | linker |
| Gly 685 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Gly 386 | - | expression tag |
| His 387 | - | expression tag |
| His 388 | - | expression tag |
| His 389 | - | expression tag |
| His 390 | - | expression tag |
| His 391 | - | expression tag |
| His 392 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 94621.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1061.0 | |
| All* | Total formula weight | 95682.9 |
