3QCM

Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 2-[(3,4-dichlorobenzyl)sulfanyl]-4-{[3-({N-[2-(methylamino)ethyl]glycyl}amino)phenyl]ethynyl}benzoic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Receptor-type tyrosine-protein phosphatase gamma	polymer	310	35735.6	2	UniProt (P23470) Pfam (PF00102) In PDB	Homo sapiens (human)	Protein-tyrosine phosphatase gamma, R-PTP-gamma
2	A, B	2-[(3,4-dichlorobenzyl)sulfanyl]-4-{[3-({N-[2-(methylamino)ethyl]glycyl}amino)phenyl]ethynyl}benzoic acid	non-polymer		542.5	2	Chemie (NXW)
3	A, B	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
4		water	water		18.0	93	Chemie (HOH)

Sequence modifications

A, B: 825 - 1128 (UniProt: P23470)

PDB	External Database	Details
Gly 819	-	expression tag
Ser 820	-	expression tag
His 821	-	expression tag
Met 822	-	expression tag
Gly 823	-	expression tag
Ser 824	-	expression tag
Ile 948	Val 948	engineered mutation
Thr 970	Ser 970	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71471.2
Non-Polymers*	Number of molecules	4
	Total formula weight	1475.4
All*	Total formula weight	72946.7

*Water molecules are not included.