Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE NXW A 2001 |
| Chain | Residue |
| A | TYR841 |
| A | ARG1066 |
| A | THR1069 |
| A | TYR1070 |
| A | GLU1107 |
| A | GLN1108 |
| A | ILE1110 |
| A | PHE1111 |
| A | ASP1114 |
| A | GLN845 |
| A | ILE950 |
| A | TYR1023 |
| A | TRP1026 |
| A | VAL1031 |
| A | PRO1032 |
| A | VAL1038 |
| A | PHE1041 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE MES A 2051 |
| Chain | Residue |
| A | TYR880 |
| A | ASN882 |
| A | ILE883 |
| A | LYS960 |
| A | SER1061 |
| A | ALA1062 |
| A | GLN1104 |
| A | HOH2146 |
| A | HOH2147 |
| A | HOH2149 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE NXW B 2001 |
| Chain | Residue |
| B | TYR841 |
| B | GLN845 |
| B | ILE950 |
| B | TYR1023 |
| B | TRP1026 |
| B | VAL1031 |
| B | PRO1032 |
| B | VAL1038 |
| B | PHE1041 |
| B | ARG1066 |
| B | THR1069 |
| B | TYR1070 |
| B | GLU1107 |
| B | GLN1108 |
| B | ILE1110 |
| B | PHE1111 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE MES B 2051 |
| Chain | Residue |
| A | GLN1013 |
| B | TYR880 |
| B | ASN882 |
| B | ILE883 |
| B | LYS960 |
| B | SER1061 |
| B | ALA1062 |
| B | GLN1104 |
| B | HOH2122 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGvgRTG |
| Chain | Residue | Details |
| A | VAL1058-GLY1068 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10044","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
