3Q4F

Crystal structure of xrcc4/xlf-cernunnos complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, E, F (E, F, A, B)	Non-homologous end-joining factor 1	polymer	230	26286.3	4	UniProt (Q9H9Q4) Pfam (PF09302) Pfam (PF21928)	Homo sapiens (human)	Protein cernunnos, XRCC4-like factor
2	C, D, G, H (C, D, G, H)	DNA repair protein XRCC4	polymer	186	21593.2	4	UniProt (Q13426) Pfam (PF06632) Pfam (PF21924)	Homo sapiens (human)	X-ray repair cross-complementing protein 4

Sequence modifications

E, F, A, B: 1 - 224 (UniProt: Q9H9Q4)

PDB	External Database	Details
His 225	-	expression tag
His 226	-	expression tag
His 227	-	expression tag
His 228	-	expression tag
His 229	-	expression tag
His 230	-	expression tag

C, D, G, H: 1 - 157 (UniProt: Q13426)

PDB	External Database	Details
Met -28	-	expression tag
Ser -27	-	expression tag
Tyr -26	-	expression tag
Tyr -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
Leu -18	-	expression tag
Glu -17	-	expression tag
Ser -16	-	expression tag
Thr -15	-	expression tag
Ser -14	-	expression tag
Leu -13	-	expression tag
Tyr -12	-	expression tag
Lys -11	-	expression tag
Lys -10	-	expression tag
Ala -9	-	expression tag
Gly -8	-	expression tag
Phe -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	191518.1
All*	Total formula weight	191518.1

*Water molecules are not included.