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3PZE

JNK1 in complex with inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mitogen-activated protein kinase 8polymer35841347.81UniProt (P45983)
Pfam (PF00069)
Homo sapiens (human)MAP kinase 8, MAPK 8, JNK-46, Stress-activated protein kinase 1, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1
2B, C, D, E
(A)
SULFATE IONnon-polymer96.14Chemie (SO4)
3F
(A)
3-(carbamoylamino)-5-phenylthiophene-2-carboxamidenon-polymer261.31Chemie (CFK)
4G
(A)
waterwater18.0177Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight41347.8
Non-Polymers*Number of molecules5
Total formula weight645.6
All*Total formula weight41993.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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