3PT6
Crystal structure of mouse DNMT1(650-1602) in complex with DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (A, B) | DNA (cytosine-5)-methyltransferase 1 | polymer | 954 | 108040.2 | 2 | UniProt (P13864) Pfam (PF02008) Pfam (PF01426) Pfam (PF00145) | Mus musculus (mouse) | Dnmt1, Met-1, DNA methyltransferase MmuI, DNA MTase MmuI, M.MmuI, MCMT |
| 2 | B, D (C, D) | DNA (5'-D(*TP*CP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*CP*CP*GP*CP*AP*GP*G)-3') | polymer | 19 | 5782.7 | 2 | |||
| 3 | C, E (I, J) | DNA (5'-D(*CP*CP*TP*GP*CP*GP*GP*AP*GP*GP*CP*TP*CP*AP*CP*GP*GP*GP*A)-3') | polymer | 19 | 5871.8 | 2 | |||
| 4 | G, M (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 5 | H, I, J, K, L... (A, B) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 6 | Q, R (A, B) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A, B: 650 - 1602 (UniProt: P13864)
| PDB | External Database | Details |
|---|---|---|
| Ser 649 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 239389.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1292.1 | |
| All* | Total formula weight | 240681.5 |
