3PHX
OTU Domain of Crimean Congo Hemorrhagic Fever Virus in complex with ISG15
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | RNA-directed RNA polymerase L | polymer | 185 | 21011.6 | 1 | UniProt (Q6TQR6) Pfam (PF02338) In PDB | Crimean-Congo hemorrhagic fever virus (CCHFV) | Protein L, Large structural protein, Replicase, Transcriptase, Ubiquitin thiolesterase, RNA-directed RNA polymerase |
| 2 | B | Ubiquitin-like protein ISG15 | polymer | 79 | 8985.3 | 1 | UniProt (P05161) Pfam (PF00240) In PDB | Homo sapiens (human) | Interferon-induced 15 kDa protein, Interferon-induced 17 kDa protein, IP17, Ubiquitin cross-reactive protein, hUCRP |
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
| 4 | A, B | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
| 5 | B | ETHANAMINE | non-polymer | 45.1 | 1 | Chemie (NEH) | |||
| 6 | water | water | 18.0 | 192 | Chemie (HOH) |
Sequence modifications
A: 1 - 183 (UniProt: Q6TQR6)
B: 79 - 156 (UniProt: P05161)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | EXPRESSION TAG |
| Pro 0 | - | EXPRESSION TAG |
| PDB | External Database | Details |
|---|---|---|
| Met 78 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 29996.8 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 950.1 | |
| All* | Total formula weight | 30946.9 |
