3PGW

Crystal structure of human U1 snRNP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, J (A, P)	U1-A	polymer	282	31319.5	2	UniProt (P09012) Pfam (PF00076)	Homo sapiens (human)	U1 snRNP A, U1 small nuclear ribonucleoprotein A, U1A
2	B, K (S, L)	U1-70K	polymer	437	51683.2	2	UniProt (P08621) Pfam (PF12220) Pfam (PF00076)	Homo sapiens (human)	U1 snRNP 70 kDa, snRNP70, U1 small nuclear ribonucleoprotein 70 kDa
3	C, L (Z, W)	Sm-D3	polymer	126	13940.3	2	UniProt (P62318) Pfam (PF01423)	Homo sapiens (human)	Small nuclear ribonucleoprotein Sm D3, snRNP core protein D3
4	D, M (B, Q)	Sm B	polymer	231	23686.0	2	UniProt (Q66K91) Pfam (PF01423) UniProt (by SIFTS) (P14678)	Homo sapiens (human)	Small nuclear ribonucleoprotein polypeptides B and B1
5	E, N (X, U)	Sm-D1	polymer	119	13310.7	2	UniProt (P62314) Pfam (PF01423)	Homo sapiens (human)	Small nuclear ribonucleoprotein Sm D1, Sm-D autoantigen, snRNP core protein D1
6	F, O (Y, V)	Sm-D2	polymer	118	13551.9	2	UniProt (P62316) Pfam (PF01423)	Homo sapiens (human)	Small nuclear ribonucleoprotein Sm D2, snRNP core protein D2
7	G, P (F, I)	Sm-F	polymer	86	9734.2	2	UniProt (P62306) Pfam (PF01423)	Homo sapiens (human)	snRNP-F, Sm protein F, Small nuclear ribonucleoprotein F, SmF
8	H, Q (E, H)	Sm-E	polymer	92	10817.6	2	UniProt (P62304) Pfam (PF01423)	Homo sapiens (human)	snRNP-E, Sm protein E, Small nuclear ribonucleoprotein E, SmE
9	I, R (G, J)	Sm G	polymer	76	8508.1	2	UniProt (D6W5G6) Pfam (PF01423) UniProt (by SIFTS) (P62308)	Homo sapiens (human)	Small nuclear ribonucleoprotein polypeptide G, isoform CRA_a
10	S, T (R, N)	U1 snRNA	polymer	164	52697.1	2		Homo sapiens (human)
11	U, V (D, M)	DNA 5'-D(*AP*GP*GP*TP*AP*AP*GP*TP*A)-3'	polymer	9	2803.9	2

Contents of the asymmetric unit

Polymers	Number of chains	22
	Total formula weight	464104.8
All*	Total formula weight	464104.8

*Water molecules are not included.