3PDC

Crystal structure of hydrolase domain of human soluble epoxide hydrolase complexed with a benzoxazole inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Epoxide hydrolase 2	polymer	344	39312.0	2	UniProt (P34913) Pfam (PF00561)	Homo sapiens (human)	Cytosolic epoxide hydrolase, CEH, Epoxide hydratase, Soluble epoxide hydrolase, SEH
2	C, D (A, B)	N-(5-chloro-1,3-benzoxazol-2-yl)-2-cyclopentylacetamide	non-polymer		278.7	2	Chemie (ZYI)
3	E, F (A, B)	water	water		18.0	191	Chemie (HOH)

Sequence modifications

A, B: 224 - 547 (UniProt: P34913)

PDB	External Database	Details
Met 203	-	expression tag
Gly 204	-	expression tag
Ser 205	-	expression tag
Ser 206	-	expression tag
His 207	-	expression tag
His 208	-	expression tag
His 209	-	expression tag
His 210	-	expression tag
His 211	-	expression tag
His 212	-	expression tag
Ser 213	-	expression tag
Ser 214	-	expression tag
Gly 215	-	expression tag
Leu 216	-	expression tag
Val 217	-	expression tag
Pro 218	-	expression tag
Arg 219	-	expression tag
Gly 220	-	expression tag
Ser 221	-	expression tag
His 222	-	expression tag
Met 223	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	78624.0
Non-Polymers*	Number of molecules	2
	Total formula weight	557.5
All*	Total formula weight	79181.5

*Water molecules are not included.