3P8E

Crystal structure of human DIMETHYLARGININE DIMETHYLAMINOHYDROLASE-1 (DDAH-1) covalently bound with N5-(1-iminopentyl)-L-ornithine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	polymer	308	33623.5	2	UniProt (O94760) Pfam (PF19420)	Homo sapiens (human)	DDAH-1, Dimethylarginine dimethylaminohydrolase 1, DDAHI, Dimethylargininase-1
2	C, D (A, B)	N~5~-[(1S)-1-aminopentyl]-L-ornithine	non-polymer		217.3	2	Chemie (LN7)
3	E, F (A, B)	water	water		18.0	49	Chemie (HOH)

Sequence modifications

A, B: 1 - 285 (UniProt: O94760)

PDB	External Database	Details
Met -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
Ser -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Leu -9	-	expression tag
Val -8	-	expression tag
Pro -7	-	expression tag
Arg -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
His -3	-	expression tag
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67247.0
Non-Polymers*	Number of molecules	2
	Total formula weight	434.6
All*	Total formula weight	67681.6

*Water molecules are not included.