3P3N
Factor inhibiting HIF-1 Alpha in complex with Notch 1 fragment mouse notch (1930-1949) peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hypoxia-inducible factor 1-alpha inhibitor | polymer | 349 | 40328.3 | 1 | UniProt (Q9NWT6) Pfam (PF13621) | Homo sapiens (human) | Hypoxia-inducible factor asparagine hydroxylase, Factor inhibiting HIF-1, FIH-1 |
| 2 | B (B) | Notch 1 protein | polymer | 20 | 2161.3 | 1 | UniProt (Q8K428) UniProt (by SIFTS) (Q01705) | Mus musculus | |
| 3 | C (A) | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) | |||
| 4 | D, E (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | F (A) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) | |||
| 6 | G, H, I, J (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 7 | K, L (A, B) | water | water | 18.0 | 166 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42489.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 762.4 | |
| All* | Total formula weight | 43252.0 |
