3P0Q
Human Tankyrase 2 - Catalytic PARP domain in complex with an inhibitor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Tankyrase-2 | polymer | 240 | 27299.8 | 2 | UniProt (Q9H2K2) Pfam (PF00644) In PDB | Homo sapiens (human) | Poly(ADP-ribose) polymerase, TANK2, Tankyrase II, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase-like protein, Tankyrase-related protein, Poly [ADP-ribose] polymerase 5B |
2 | A, C | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
3 | A, C | N-[2-(4-chlorophenyl)ethyl]-6-methyl[1,2,4]triazolo[4,3-b]pyridazin-8-amine | non-polymer | 287.7 | 2 | Chemie (NNL) | |||
4 | A, C | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
5 | A, C | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
6 | water | water | 18.0 | 337 | Chemie (HOH) |
Sequence modifications
A, C: 946 - 1162 (UniProt: Q9H2K2)
PDB | External Database | Details |
---|---|---|
Met 923 | - | expression tag |
His 924 | - | expression tag |
His 925 | - | expression tag |
His 926 | - | expression tag |
His 927 | - | expression tag |
His 928 | - | expression tag |
His 929 | - | expression tag |
Ser 930 | - | expression tag |
Ser 931 | - | expression tag |
Gly 932 | - | expression tag |
Val 933 | - | expression tag |
Asp 934 | - | expression tag |
Leu 935 | - | expression tag |
Gly 936 | - | expression tag |
Thr 937 | - | expression tag |
Glu 938 | - | expression tag |
Asn 939 | - | expression tag |
Leu 940 | - | expression tag |
Tyr 941 | - | expression tag |
Phe 942 | - | expression tag |
Gln 943 | - | expression tag |
Ser 944 | - | expression tag |
Met 945 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 54599.5 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 1136.5 | |
All* | Total formula weight | 55736.1 |