3OTK
Structure and mechanisim of core 2 beta1,6-n-acetylglucosaminyltransferase: a Metal-ion independent gt-a glycosyltransferase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase | polymer | 391 | 45303.9 | 4 | UniProt (Q09324) Pfam (PF02485) | Mus musculus (mouse) | Core 2-branching enzyme, Core2-GlcNAc-transferase, C2GNT |
| 2 | E, F (E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 3 | G, H (A) | HEPTANE-1,2,3-TRIOL | non-polymer | 148.2 | 2 | Chemie (HTO) | |||
| 4 | I, N (A, C) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | J, L, O, Q (A, B, C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 6 | K, M, P, R (A, B, C, D) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 4 | Chemie (UDP) | |||
| 7 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 533 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 38 - 428 (UniProt: Q09324)
| PDB | External Database | Details |
|---|---|---|
| Ser 217 | Cys 217 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 181215.5 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1141.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2843.9 | |
| All* | Total formula weight | 185200.4 |
