3OQ3
Structural Basis of Type-I Interferon Sequestration by a Poxvirus Decoy Receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interferon alpha-5 | polymer | 166 | 18985.8 | 1 | UniProt (P07349) Pfam (PF00143) | Mus musculus (mouse) | IFN-alpha-5 |
| 2 | B (B) | IFN-alpha/beta binding protein C12R | polymer | 329 | 37626.4 | 1 | UniProt (Q9JFS5) Pfam (PF13895) Pfam (PF00047) | Ectromelia virus | Interferon alpha/beta receptor, Soluble interferon-alpha/beta receptor |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E, F, I, J (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 6 | G, H (B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 7 | K, L (B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 8 | M, N (A, B) | water | water | 18.0 | 361 | Chemie (HOH) |
Sequence modifications
B: 1 - 328 (UniProt: Q9JFS5)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56612.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 943.8 | |
| All* | Total formula weight | 57556.0 |
