3OOI
Crystal Structure of Human Histone-Lysine N-methyltransferase NSD1 SET domain in Complex with S-adenosyl-L-methionine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific | polymer | 232 | 26526.2 | 1 | UniProt (Q96L73) Pfam (PF17907) Pfam (PF00856) | Homo sapiens (human) | Nuclear receptor-binding SET domain-containing protein 1, H3-K36-HMTase, H4-K20-HMTase |
| 2 | B, C, D (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | E, F (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | G (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 5 | H (A) | water | water | 18.0 | 288 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: Q96L73)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 26526.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 786.8 | |
| All* | Total formula weight | 27313.0 |
