3OLR

PTPN22 in complex with consensus phospho-tyrosine peptide 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Tyrosine-protein phosphatase non-receptor type 22	polymer	313	36743.1	4	UniProt (Q9Y2R2) Pfam (PF00102) In PDB	Homo sapiens (human)	Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, Lymphoid phosphatase, LyP
2	E, F, G, H	SKAP2	polymer	9	1246.1	4
3		water	water		18.0	395	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 294 (UniProt: Q9Y2R2)

PDB	External Database	Details
His -19	-	EXPRESSION TAG
His -18	-	EXPRESSION TAG
His -17	-	EXPRESSION TAG
His -16	-	EXPRESSION TAG
His -15	-	EXPRESSION TAG
His -14	-	EXPRESSION TAG
Ser -13	-	EXPRESSION TAG
Ser -12	-	EXPRESSION TAG
Gly -11	-	EXPRESSION TAG
Leu -10	-	EXPRESSION TAG
Val -9	-	EXPRESSION TAG
Pro -8	-	EXPRESSION TAG
Arg -7	-	EXPRESSION TAG
Gly -6	-	EXPRESSION TAG
Ser -5	-	EXPRESSION TAG
His -4	-	EXPRESSION TAG
Met -3	-	EXPRESSION TAG
Ala -2	-	EXPRESSION TAG
Ser -1	-	EXPRESSION TAG
Ser 227	Cys 227	ENGINEERED MUTATION

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	151956.8
All*	Total formula weight	151956.8

*Water molecules are not included.