3OLR

PTPN22 in complex with consensus phospho-tyrosine peptide 1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004725	molecular_function	protein tyrosine phosphatase activity
A	0004726	molecular_function	non-membrane spanning protein tyrosine phosphatase activity
A	0006470	biological_process	protein dephosphorylation
A	0016311	biological_process	dephosphorylation
B	0004725	molecular_function	protein tyrosine phosphatase activity
B	0004726	molecular_function	non-membrane spanning protein tyrosine phosphatase activity
B	0006470	biological_process	protein dephosphorylation
B	0016311	biological_process	dephosphorylation
C	0004725	molecular_function	protein tyrosine phosphatase activity
C	0004726	molecular_function	non-membrane spanning protein tyrosine phosphatase activity
C	0006470	biological_process	protein dephosphorylation
C	0016311	biological_process	dephosphorylation
D	0004725	molecular_function	protein tyrosine phosphatase activity
D	0004726	molecular_function	non-membrane spanning protein tyrosine phosphatase activity
D	0006470	biological_process	protein dephosphorylation
D	0016311	biological_process	dephosphorylation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160, ECO:0000255|PROSITE-ProRule:PRU10044

Chain	Residue	Details
A	SER227
B	SER227
C	SER227
D	SER227

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site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|Ref.20

Chain	Residue	Details
A	SER227
A	GLN274
B	SER227
B	GLN274
C	SER227
C	GLN274
D	SER227
D	GLN274

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site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: Phosphoserine; by PKC/PRKCD => ECO:0000269|PubMed:18056643

Chain	Residue	Details
A	SER35
B	SER35
C	SER35
D	SER35

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