3OB7
Human Thymidylate Synthase R163K with Cys 195 covalently modified by Glutathione
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Thymidylate synthase | polymer | 313 | 35734.9 | 5 | UniProt (P04818) Pfam (PF00303) | Homo sapiens (human) | TSase, TS |
| 2 | F, I (A, D) | GLUTATHIONE | non-polymer | 307.3 | 2 | Chemie (GSH) | |||
| 3 | G, H, J (A, C, E) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 4 | K, L, M, N, O (A, B, C, D, E) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 313 (UniProt: P04818)
| PDB | External Database | Details |
|---|---|---|
| Lys 163 | Arg 163 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 178674.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 899.6 | |
| All* | Total formula weight | 179574.2 |
