3O4O
Crystal structure of an Interleukin-1 receptor complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-1 beta | polymer | 158 | 17807.3 | 1 | UniProt (P01584) Pfam (PF00340) | Homo sapiens (human) | IL-1beta, IL-1 beta, Catabolin |
| 2 | B (C) | Interleukin-1 receptor type 2 | polymer | 339 | 38945.1 | 1 | UniProt (P27930) Pfam (PF00047) | Homo sapiens (human) | IL-1RII, IL-1RT-2, IL-1RT2, IL-1R-2, Interleukin-1 receptor type II, Interleukin-1 receptor beta, IL-1R-beta, CD121 antigen-like family member B, CDw121b |
| 3 | C (B) | Interleukin-1 receptor accessory protein | polymer | 339 | 39258.6 | 1 | UniProt (Q9NPH3) Pfam (PF18452) | Homo sapiens (human) | IL-1RAcP, IL-1 receptor accessory protein, Interleukin-1 receptor 3, IL-1R-3, IL-1R3 |
| 4 | D, E (D, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | F, G, H, I (C, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
A: 1 - 153 (UniProt: P01584)
C: 1 - 330 (UniProt: P27930)
B: 1 - 330 (UniProt: Q9NPH3)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Pro 0 | - | expression tag |
| His 331 | - | expression tag |
| His 332 | - | expression tag |
| His 333 | - | expression tag |
| His 334 | - | expression tag |
| His 335 | - | expression tag |
| His 336 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Pro 0 | - | expression tag |
| His 331 | - | expression tag |
| His 332 | - | expression tag |
| His 333 | - | expression tag |
| His 334 | - | expression tag |
| His 335 | - | expression tag |
| His 336 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 96011.0 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 97744.6 |
