3NAI

Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	RNA dependent RNA polymerase	polymer	517	58519.5	3	UniProt (Q80J95) Pfam (PF00680)	Murine norovirus 1	RdRp
2	D, O, X (A, B, C)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
3	E, P, Y (A, B, C)	5-FLUOROURACIL	non-polymer		130.1	3	Chemie (URF)
4	AA, F, G, Q, R... (C, A, B)	MANGANESE (III) ION	non-polymer		54.9	6	Chemie (MN3)
5	BA, CA, DA, H, I... (C, A, B)	SULFATE ION	non-polymer		96.1	14	Chemie (SO4)
6	EA, N (C, A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
7	FA, GA, HA (A, B, C)	water	water		18.0	348	Chemie (HOH)

Sequence modifications

A, B, C: 4 - 509 (UniProt: Q80J95)

PDB	External Database	Details
Ala 510	-	expression tag
Ala 511	-	expression tag
Ala 512	-	expression tag
Leu 513	-	expression tag
Glu 514	-	expression tag
His 515	-	expression tag
His 516	-	expression tag
His 517	-	expression tag
His 518	-	expression tag
His 519	-	expression tag
His 520	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	175558.6
Non-Polymers*	Number of molecules	28
	Total formula weight	2321.8
All*	Total formula weight	177880.5

*Water molecules are not included.