3MXM
TREX1 3' Exonuclease V201D Aicardi-Goutieres Syndrome Mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Three prime repair exonuclease 1 | polymer | 242 | 26339.9 | 2 | UniProt (Q91XB0) | Mus musculus (mouse) | 3'-5' exonuclease TREX1 |
| 2 | C, D (C, D) | DNA (5'-D(*GP*AP*CP*G)-3') | polymer | 4 | 1215.8 | 2 | |||
| 3 | E, I, R, S (B, A, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | F, G, H, J, K... (B, A, D) | IODIDE ION | non-polymer | 126.9 | 12 | Chemie (IOD) | |||
| 5 | U, V, W, X (B, A, C, D) | water | water | 18.0 | 539 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 242 (UniProt: Q91XB0)
| PDB | External Database | Details |
|---|---|---|
| Asp 201 | Val 201 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 55111.5 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1683.2 | |
| All* | Total formula weight | 56794.7 |
