3MJH
Crystal Structure of Human Rab5A in complex with the C2H2 Zinc Finger of EEA1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Ras-related protein Rab-5A | polymer | 168 | 18801.4 | 2 | UniProt (P20339) Pfam (PF00071) In PDB | Homo sapiens (human) | |
2 | B, D | Early endosome antigen 1 | polymer | 34 | 3678.0 | 2 | UniProt (Q15075) In PDB | Homo sapiens (human) | Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2 |
3 | A, C | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
4 | A, C | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
5 | B, D | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
6 | water | water | 18.0 | 312 | Chemie (HOH) |
Sequence modifications
A, C: 16 - 183 (UniProt: P20339)
PDB | External Database | Details |
---|---|---|
Leu 79 | Gln 79 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 44958.9 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1225.8 | |
All* | Total formula weight | 46184.7 |