3MJH
Crystal Structure of Human Rab5A in complex with the C2H2 Zinc Finger of EEA1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Ras-related protein Rab-5A | polymer | 168 | 18801.4 | 2 | UniProt (P20339) Pfam (PF00071) | Homo sapiens (human) | |
| 2 | B, D (B, D) | Early endosome antigen 1 | polymer | 34 | 3678.0 | 2 | UniProt (Q15075) | Homo sapiens (human) | Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2 |
| 3 | E, H (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 4 | F, I (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G, J (B, D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 312 | Chemie (HOH) |
Sequence modifications
A, C: 16 - 183 (UniProt: P20339)
| PDB | External Database | Details |
|---|---|---|
| Leu 79 | Gln 79 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 44958.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1225.8 | |
| All* | Total formula weight | 46184.7 |
