3MJH
Crystal Structure of Human Rab5A in complex with the C2H2 Zinc Finger of EEA1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Ras-related protein Rab-5A | polymer | 168 | 18801.4 | 2 | UniProt (P20339) Pfam (PF00071) | Homo sapiens (human) | |
| 2 | B, D (B, D) | Early endosome antigen 1 | polymer | 34 | 3678.0 | 2 | UniProt (Q15075) | Homo sapiens (human) | Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2 |
| 3 | E, H (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 4 | F, I (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 5 | G, J (B, D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 312 | Chemie (HOH) |
Sequence modifications
A, C: 16 - 183 (UniProt: P20339)
| PDB | External Database | Details |
|---|---|---|
| Leu 79 | Gln 79 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 44958.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1225.8 | |
| All* | Total formula weight | 46184.7 |
