3ME2
Crystal structure of mouse RANKL-RANK complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tumor necrosis factor ligand superfamily member 11 | polymer | 171 | 19056.4 | 1 | UniProt (O35235) Pfam (PF00229) | Mus musculus (mouse) | Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE, Osteoprotegerin ligand, OPGL, Osteoclast differentiation factor, ODF |
| 2 | B (R) | Tumor necrosis factor receptor superfamily member 11A | polymer | 216 | 24018.1 | 1 | UniProt (O35305) Pfam (PF00020) Pfam (PF18278) | Mus musculus (mouse) | Receptor activator of NF-KB, Osteoclast differentiation factor receptor, ODFR, RANK |
| 3 | C, D, E, G (A, R) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 4 | F (R) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | H, I (A, R) | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence modifications
A: 158 - 316 (UniProt: O35235)
R: 26 - 210 (UniProt: O35305)
| PDB | External Database | Details |
|---|---|---|
| Gly 146 | - | expression tag |
| Pro 147 | - | expression tag |
| Leu 148 | - | expression tag |
| Gly 149 | - | expression tag |
| Ser 150 | - | expression tag |
| Pro 151 | - | expression tag |
| Glu 152 | - | expression tag |
| Phe 153 | - | expression tag |
| Pro 154 | - | expression tag |
| Gly 155 | - | expression tag |
| Arg 156 | - | expression tag |
| Arg 157 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | expression tag |
| Gly 4 | - | expression tag |
| Ser 5 | - | expression tag |
| Ser 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
| Ser 13 | - | expression tag |
| Ser 14 | - | expression tag |
| Gly 15 | - | expression tag |
| Leu 16 | - | expression tag |
| Val 17 | - | expression tag |
| Pro 18 | - | expression tag |
| Arg 19 | - | expression tag |
| Gly 20 | - | expression tag |
| Ser 21 | - | expression tag |
| His 22 | - | expression tag |
| Met 23 | - | expression tag |
| His 24 | - | expression tag |
| Met 25 | - | expression tag |
| Leu 211 | - | expression tag |
| Glu 212 | - | expression tag |
| His 213 | - | expression tag |
| His 214 | - | expression tag |
| His 215 | - | expression tag |
| His 216 | - | expression tag |
| His 217 | - | expression tag |
| His 218 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43074.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 164.8 | |
| All* | Total formula weight | 43239.3 |
