3ME2

Crystal structure of mouse RANKL-RANK complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005164	molecular_function	tumor necrosis factor receptor binding
A	0006955	biological_process	immune response
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL A 5

Chain	Residue
A	SER184
A	SER185
A	TRP186
A	LEU200
A	ASN202
A	GLY203

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 6

Chain	Residue
A	HIS188
A	ASP189
A	ARG190

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 7

Chain	Residue
A	LYS194
A	LYS281
R	LYS86

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA R 1

Chain	Residue
R	CYS134
R	ALA135
R	PHE138
R	SER161
R	VAL163
R	HOH239

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL R 219

Chain	Residue
R	HIS90
R	LYS91
R	ARG111

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Functional Information from PROSITE/UniProt

site_id	PS00652
Number of Residues	35
Details	TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Ctqerh.Yehlgr.....C..Csr.Cepgkylssk..Ctpts..DSVC

Chain	Residue	Details
R	CYS35-CYS69

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site_id	PS01186
Number of Residues	16
Details	EGF_2 EGF-like domain signature 2. CaCtaGYhwnsdcecC

Chain	Residue	Details
R	CYS113-CYS128

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING:

Chain	Residue	Details
R	CYS134
R	ALA135
R	PHE138
R	SER161
R	VAL163

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site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:23039992

Chain	Residue	Details
R	ASN106

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
R	ASN175

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