3MDR

Tranylcypromine complex of Cytochrome P450 46A1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Cholesterol 24-hydroxylase	polymer	456	52125.1	2	UniProt (Q9Y6A2) Pfam (PF00067) In PDB	Homo sapiens (human)	CH24H, Cytochrome P450 46A1
2	A, B	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	2	Chemie (HEM)
3	A, B	(1R,2S)-2-phenylcyclopropanamine	non-polymer		133.2	2	Chemie (GJZ)
4		water	water		18.0	340	Chemie (HOH)

Sequence modifications

A, B: 51 - 500 (UniProt: Q9Y6A2)

PDB	External Database	Details
Met 49	-	expression tag
Ala 50	-	expression tag
His 501	-	expression tag
His 502	-	expression tag
His 503	-	expression tag
His 504	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	104250.2
Non-Polymers*	Number of molecules	4
	Total formula weight	1499.4
All*	Total formula weight	105749.5

*Water molecules are not included.