3M59
SET7/9 Y245A in complex with TAF10-K189me2 peptide and AdoHcy
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Histone-lysine N-methyltransferase SETD7 | polymer | 261 | 28951.2 | 1 | UniProt (Q8WTS6) Pfam (PF22648) Pfam (PF00856) In PDB | Homo sapiens (human) | Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, SET domain-containing protein 7, SET7/9, Lysine N-methyltransferase 7 |
| 2 | B | TAF10-K189me2 Peptide | polymer | 11 | 1282.5 | 1 | UniProt (by SIFTS) (Q12962) In PDB | Homo sapiens | |
| 3 | A | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 4 | A | COBALT (II) ION | non-polymer | 58.9 | 3 | Chemie (CO) | |||
| 5 | A | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
A: 110 - 366 (UniProt: Q8WTS6)
| PDB | External Database | Details |
|---|---|---|
| Gly 106 | - | expression tag |
| Ala 107 | - | expression tag |
| Met 108 | - | expression tag |
| Gly 109 | - | expression tag |
| Ala 245 | Tyr 245 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30233.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 929.6 | |
| All* | Total formula weight | 31163.3 |
