3M59
SET7/9 Y245A in complex with TAF10-K189me2 peptide and AdoHcy
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone-lysine N-methyltransferase SETD7 | polymer | 261 | 28951.2 | 1 | UniProt (Q8WTS6) Pfam (PF22648) Pfam (PF00856) | Homo sapiens (human) | Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, SET domain-containing protein 7, SET7/9, Lysine N-methyltransferase 7 |
| 2 | B (B) | TAF10-K189me2 Peptide | polymer | 11 | 1282.5 | 1 | UniProt (by SIFTS) (Q12962) | Homo sapiens | |
| 3 | C (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (25210495) PubChem (13792) PubChem (177678424) PubChem (44361184) PubChem (21125603) PubChem (46936206) PubChem (50989525) PubChem (25203782) PubChem (51380914) PubChem (52224398) PubChem (189149) PubChem (57544532) PubChem (439155) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (52224400) PubChem (5284331) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (71170554) PubChem (13231890) PubChem (164157219) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 4 | D, E, F (A) | COBALT (II) ION | non-polymer | 58.9 | 3 | Chemie (CO) PubChem (104729) | |||
| 5 | G, H, I, J (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) PubChem (753) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
A: 110 - 366 (UniProt: Q8WTS6)
| PDB | External Database | Details |
|---|---|---|
| Gly 106 | - | expression tag |
| Ala 107 | - | expression tag |
| Met 108 | - | expression tag |
| Gly 109 | - | expression tag |
| Ala 245 | Tyr 245 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30233.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 929.6 | |
| All* | Total formula weight | 31163.3 |
