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3LXG

Crystal structure of rat phosphodiesterase 10A in complex with ligand WEB-3

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Apolymer30835673.01UniProt (Q9QYJ6)
Pfam (PF00233)
Rattus norvegicus (rat)
2B
(A)
2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrido[3,2-e]pyrazinenon-polymer270.31Chemie (Z73)
3C
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4D
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5E
(A)
waterwater18.0118Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight35673.0
Non-Polymers*Number of molecules3
Total formula weight360.0
All*Total formula weight36033.1
*Water molecules are not included.

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PDB entries from 2025-11-05

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