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3LMS

Structure of human activated thrombin-activatable fibrinolysis inhibitor, TAFIa, in complex with tick-derived funnelin inhibitor, TCI.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Carboxypeptidase B2polymer30935835.41UniProt (Q96IY4)
Pfam (PF00246)
Homo sapiens (human)TAFI, Carboxypeptidase U, CPU, Thrombin-activable fibrinolysis inhibitor, Plasma carboxypeptidase B, pCPB
2B
(B)
Carboxypeptidase inhibitorpolymer747807.01UniProt (Q5EPH2)
Pfam (PF10468)
Rhipicephalus bursatick-derived funnelin inhibitor, TCI
3C
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4D
(A)
GLYCINEnon-polymer75.11Chemie (GLY)
5E, F, G, M
(A, B)
GLYCEROLnon-polymer92.14Chemie (GOL)
6H, I, N
(A, B)
CHLORIDE IONnon-polymer35.53Chemie (CL)
7J
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
8K, L
(A)
POTASSIUM IONnon-polymer39.12Chemie (K)
9O, P
(A, B)
waterwater18.088Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight43642.4
Non-Polymers*Number of molecules12
Total formula weight733.5
All*Total formula weight44375.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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