3LMS
Structure of human activated thrombin-activatable fibrinolysis inhibitor, TAFIa, in complex with tick-derived funnelin inhibitor, TCI.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Carboxypeptidase B2 | polymer | 309 | 35835.4 | 1 | UniProt (Q96IY4) Pfam (PF00246) | Homo sapiens (human) | TAFI, Carboxypeptidase U, CPU, Thrombin-activable fibrinolysis inhibitor, Plasma carboxypeptidase B, pCPB |
2 | B (B) | Carboxypeptidase inhibitor | polymer | 74 | 7807.0 | 1 | UniProt (Q5EPH2) Pfam (PF10468) | Rhipicephalus bursa | tick-derived funnelin inhibitor, TCI |
3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
4 | D (A) | GLYCINE | non-polymer | 75.1 | 1 | Chemie (GLY) | |||
5 | E, F, G, M (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
6 | H, I, N (A, B) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
7 | J (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
8 | K, L (A) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
9 | O, P (A, B) | water | water | 18.0 | 88 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 43642.4 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 733.5 | |
All* | Total formula weight | 44375.9 |