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3LBJ

Structure of human MDMX protein in complex with a small molecule inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(E)
Protein Mdm4polymer9010292.11UniProt (O15151)Homo sapiens (human)p53-binding protein Mdm4, Mdm2-like p53-binding protein, Protein Mdmx, Double minute 4 protein
2B, C
(E)
N-[(3S)-1-({6-chloro-3-[1-(4-chlorobenzyl)-4-phenyl-1H-imidazol-5-yl]-1H-indol-2-yl}carbonyl)pyrrolidin-3-yl]-N,N',N'-trimethylpropane-1,3-diaminenon-polymer629.62Chemie (WW8)
3D
(E)
SULFATE IONnon-polymer96.11Chemie (SO4)
4E
(E)
waterwater18.0113Chemie (HOH)
Sequence modifications
E: 23 - 111 (UniProt: O15151)
PDBExternal DatabaseDetails
Met 22-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight10292.1
Non-Polymers*Number of molecules3
Total formula weight1355.3
All*Total formula weight11647.4
*Water molecules are not included.

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PDB entries from 2025-06-18

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