3LBJ

Structure of human MDMX protein in complex with a small molecule inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0005634	cellular_component	nucleus
E	0043066	biological_process	negative regulation of apoptotic process
E	0051726	biological_process	regulation of cell cycle

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE WW8 E 1

Chain	Residue
E	HOH21
E	ASP94
E	PRO95
E	PRO95
E	LEU98
E	TYR99
E	HOH161
E	HOH173
E	HOH211
E	MET53
E	HIS54
E	GLY57
E	ILE60
E	TYR66
E	GLN71
E	VAL92
E	LYS93

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE WW8 E 112

Chain	Residue
E	VAL27
E	VAL49
E	VAL49
E	TYR99
E	TYR99
E	LEU102
E	ARG103
E	HOH125
E	HOH206

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site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 E 113

Chain	Residue
E	HOH15
E	HOH15
E	HOH15
E	GLN68
E	GLN68
E	GLN68
E	HOH168
E	HOH168
E	HOH168

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